The father was a prominent man in the city of London, but subsequently, for some unknown cause, was imprisoned for thirteen years; he was released by the efforts of his brother-in-law Sir Thomas Myddelton.
[1][2] Wye entered Queen's College, Oxford, as a commoner in Easter term 1619, but did not graduate; subsequently he is said to have studied law at Gray's Inn, but his name does not appear in the register.
About 1625 he returned to Oxford "purposely for the benefit of the public library and conversation with learned men" (Wood).
He also acted as tutor in Latin and French, but latterly fell into a state of misery and apparently poverty.
He was alive in 1640, and Wood attributes to him Somnia Allegorica, by W. Salton (2nd edition 1661), no copy of which can be traced.