It makes its way west from Laramie across the plains, and rises over the Medicine Bow Mountains.

Six miles east of Centennial, 130 intersects Wyoming Highway 11 which provides a route to Albany.

From there Highway 130 travels 17 miles (27 km) in a relatively due east direction over rolling hills.

[citation needed] Shortly after, Snowy Range Road (WYO 130/WYO 230) has an interchange with I-80 (Exit 311).

Originally Highway 130 traveled southeast along the Carbon County Route 504 path to Ryan Park.