Wyoming Highway 190 begins its western end at the small settlement of Barnum, located southwest of Kaycee.

[2] Named Barnum Road, Highway 190 travels roughly east-northeast toward Kaycee following the Middle Fork of the Powder River.

[3] At 9.66 miles, WYO 190 reaches it eastern end at Wyoming Highway 191 (Mayoworth Road) in Kaycee.

[4] Exit 254 of I-25/US 87 can be accessed via WYO 191 less than a mile east of Highway 190's terminus.

Wyoming Highway 190 provides access to the Middle Fork Recreation Area near Barnum.