Wyoming Highway 216 (WYO 216), Albin Road, is a 18.54-mile (29.84 km) state highway in the northeastern part of Laramie County, Wyoming, United States, that connects U.S. Route 85 (US 85), south-southwest of Meriden with County Road 164 (CR 164) at the Nebraska state line (east of Albin).

WYO 216 begins its west end at an intersection with US 85 that is located 26 miles (42 km) northeast of the Interstate 25/US 85 split.

[1] WYO 216 travels east intersecting Wyoming Highway 213 (Burns North Road) after just 3.4 miles (5.5 km).

[2] WYO 216 continues east, passing through Albin between 15.83 and 16.18 miles (25.48 and 26.04 km).

[2] The Wyoming Highway 216 designation was originally commissioned in 1926 in Weston and Crook counties.