Term limits were declared unconstitutional by the Wyoming Supreme Court in 2004, overturning a decade-old law that had restricted Senators to three terms (twelve years).

Like other upper houses of state and territorial legislatures and the federal U.S. Senate, the Wyoming Senate can confirm or reject gubernatorial appointments to the state cabinet, commissions, boards, or justices to the Wyoming Supreme Court.

Wyoming, along with Arizona, Maine, and Oregon, is one of the four U.S. states to have abolished the Office of the Lieutenant Governor, a position which for most upper houses of state legislatures and indeed for the U.S. Congress (with the Vice President) is the head of the legislative body.

Instead, a separate position of Senate President is in place, removed from the Wyoming executive branch.

The current Senate President is Republican Ogden Driskill of District 1 (Devils Tower).