XHMLS-FM (91.3 MHz) is a radio station in Matamoros, Tamaulipas, Mexico.

XHMLS-FM is among the oldest FM stations in northeast Mexico.

It received its concession on August 11, 1960, and was owned by Manuel L. Salinas.

Salinas died later in the 1960s, and his successors received control of the station in 1967.

In 1986, XHMLS was sold to Radiodifusoras Unidas Mexicanas de Matamoros.