[3] Van Tulleken has presented many documentaries, including an episode of Horizon discussing male suicide[4] and a BBC programme on the European migrant crisis.

[5] He can often be seen offering up his own body for science experimentation in diet show How to Lose Weight Well, as well as in BBC Horizon episodes "Sugar vs Fat"[6] and "Is Binge Drinking Really That Bad?

"[7] As of July 2023, he was appearing regularly on the BBC1 weekday programme Morning Live, providing a variety of medical advice.

He is descended from Jan van Hoogenhouck Tulleken [nl] (1762–1851), a Dutch rear-admiral who was later raised to the nobility with the title of Jonkheer (equivalent of a Baronet).

[10] Van Tulleken is married to doctor Dolly Theis, a visiting researcher at MRC Epidemiology Unit, University of Cambridge and former Conservative Party candidate for Vauxhall in the 2017 general election.