Xerxes II (/ˈzɜːrksiːz/; Old Persian: 𐎧𐏁𐎹𐎠𐎼𐏁𐎠 Xšayār̥šā; Ancient Greek: Ξέρξης Xérxēs; died 424 BC) was a Persian king who was very briefly a ruler of the Achaemenid Empire, as the son and successor of Artaxerxes I.

After a reign of forty-five days—where he only had control over the Persian heartlands—he was assassinated in 424 BC by his half-brother Sogdianus, who in turn was murdered by Darius II six months later.

Ochus' first inscription as Darius II can be dated to January 10, 423 BC.

He was murdered while drunk by Sogdianus, with help from Pharnacyas and Menostanes, who had great influence over him according to Ctesias.

Darius II became the sole ruler of the Persian Empire and reigned until 404 BC.