Xoliswa Sithole (born 31 December 1968) is a South African actress and documentary filmmaker, raised in Zimbabwe.

As a documentary filmmaker, Xoliswa Sithole created and starred in Shouting Silent (2002, 2011), a film about her own family's experience with HIV/AIDS,[3][4] and directed Zimbabwe's Forgotten Children (2010).

She was associate producer on The Orphans of Nkandla (2004), making Sithole the first South African woman to win a BAFTA award.

"I have only one desire in life," she told interviewer Audrey McCluskey, "Only one – to create images that change the world.

"[9] Acting appearances by Sithole include roles in the films Cry Freedom (1987), Mandela (1987, television), Fools, and Chikin Biznis.