Yōsuke Isozaki (礒崎 陽輔, Isozaki Yōsuke, born 9 October 1957) is a Japanese politician of the Liberal Democratic Party and a member of the House of Councillors in the Diet.

A native of Ōita, Ōita, he joined the Ministry of Home Affairs after graduating from the University of Tokyo in 1982.

After leaving the ministry in 2006, he was elected to the House of Councillors for the first time in 2007.

He is affiliated with the revisionist lobby Nippon Kaigi.

This article about a Japanese politician born in the 1950s is a stub.