Dos Santos was discovered by Palmeiras, and played for Paulistano from 2016 to 2020 and Flamengo from 2020 to 2022 before moving to German club Ratiopharm Ulm.

Yago won the 2023 German BBL championship with Ulm, while being named Finals MVP as well.

[1][2] From 2020 to 2022, Yago played two seasons with Flamengo, with whom he won the 2022 FIBA Intercontinental Cup, as well as two NBB championships.

[3] He was instrumental in helping Ulm win its first ever German championship in 2023 and received Bundesliga Finals MVP honours.

[5] On July 17, 2023, Yago signed a three-year contract with Serbian powerhouse KK Crvena zvezda.