[10] By the spring of 1968, West Coast was operating Douglas DC-9-10 jet service nonstop from the airport to Seattle Boeing Field, Portland and Pasco as well as direct, no change of plane DC-9 jet flights to San Francisco (SFO), Spokane, Eugene and Medford in addition to flying Fairchild F-27 turboprop service to a number of regional destinations.

[12] In 1975, Hughes Airwest was operating all of its flights from the airport with Douglas DC-9-10 and McDonnell Douglas DC-9-30 jets with nonstop service to Seattle/Tacoma International Airport (SEA) and Pasco in addition to direct, no change of plane DC-9 jet flights to Los Angeles (LAX), Orange County Airport near Santa Ana, CA, Salt Lake City, Phoenix, Tucson, Portland, OR, Santa Maria, CA and Eugene and was also operating direct, no change of plane DC-9 service to two international destinations: Guadalajara, Mexico and Mazatlan, Mexico.

[18] According to the Official Airline Guide (OAG), Cascade and Horizon were operating a combined total of thirteen nonstop flights a day on weekdays from Seattle/Tacoma to Yakima in February 1985.

[21] That same year, PSA was acquired by and merged into USAir which in late 1988 was operating McDonnell Douglas MD-80 jetliners twice a day nonstop from Seattle/Tacoma with both of these flights originating in San Francisco with twice daily jet service from SFO to Yakima thus being flown on a direct one stop basis.

[22] According to the OAG, Horizon Air, United Express and USAir were operating a combined total of 19 nonstop flights every weekday from Seattle/Tacoma to Yakima in late 1988.

In the year ending December 31, 2022, the airport had 35,588 aircraft operations, average 97 per day, 80% general aviation, 10% military, 7% air taxi and 3% airline.

The airport has one full-service fixed-base operator (FBO), McCormick Air Center, which provides hangar leasing, aircraft rental, flight instruction, and fuel.

Yakima Air Terminal is designated as the primary diversion site for flights unable to reach Seattle–Tacoma International Airport.

In December 2023, an Airbus A330 on an international Delta Air Lines flight from London Heathrow Airport landed at Yakima due to heavy fog in the Seattle area.

It was the largest commercial airliner to land at the airport; due to the lack of customs facilities, passengers were processed by officials who arrived from Western Washington by car.