Yates City is a village in Knox County, Illinois, United States.

Illinois Route 8 passes through the center of the village, leading east 2.5 miles (4.0 km) to Elmwood and west 7 miles (11 km) to Illinois Route 97 near Maquon.

Galesburg, the Knox county seat, is 25 miles (40 km) northwest of Yates City.

According to the 2010 census, Yates City has a total area of 0.52 square miles (1.35 km2), all land.

27.8% of all households were made up of individuals, and 16.1% had someone living alone who was 65 years of age or older.