The Ybor Factory Building is a historic site in Tampa, Florida, United States located at 1911 North 13th Street.

The factory was built in 1886 by Vicente Martinez-Ybor as he moved the production of his Príncipe de Gales ("Prince of Wales") cigar line from Key West to the new company town he founded just northeast of Tampa in 1885.

The headquarters of Ybor's holding company was directly across 9th Avenue in the El Pasaje building, which was constructed at about the same time.

Over the next few decades, the buildings were vacant, then were used as gallery and studio space for artists, then converted to a festival marketplace called Ybor Square in the mid-1970s.

In 2010, the Church of Scientology bought the building for $7.05 million to consolidate its existing facilities present in Ybor City and West Tampa.