[1] Yeghishe Manoukian College was founded in 1963 under the name of Mardikian Kindergarten-Elementary School.

The founder of the school is believed to be Catholicos Sahag A. Khabian in the 1930s.

In the course of 1984–1985 academic year, Catholicos Karekin the second comes to the rescue of the schools situation.

The 10,000 m2 land in Dbayyeh, bought by the handsome donation of Vatche Manoukian and put under the disposal of the Catholicosate of Cilicia, along with the school buildings located on the property are given to the Mardikian School to transport there.

For the 1985–1986 academic year, Papken Papazian and Manoushag Boyadjian were invited to become the principals of the school.