She started working as a teacher but later continued her career in public sector as main advisor at the regional Department of Indigenous People Affairs.

[3] She also won a primary for Duma of Chukotka Autonomous Okrug, finishing ahead of Rudchenko in a party list contest.

In the State Duma Yevtyukhova joined United Russia faction and was appointed to the Committee on Russian Far East and Arctic Development.

Two days later the European Union placed sanctions on all 351 State Duma members who voted to approve a letter to Putin, including Yelena Yevtyukhova.

[8] On 24 March Yevtyukhova was designated by the OFAC as one of the key enablers of the Russian invasion and was put under US sanctions along with 328 fellow State Duma members.