Dendrobates leucomelas is a common poison dart frog found in the northern part of continent of South America, most notably in Venezuela.

Predominantly, these frogs have a bright yellow colouration with varying numbers of broad black stripes and/or spots that extend over the whole body.

[5] They have glandular, adhesive pads on their toes (which aid in climbing and positioning) and, in common with other species in their order, they have a short, protrudable, unnotched, sticky tongue, which extends to catch prey.

The alkaloid toxins, secreted from the frogs' skin, interfere with nerve impulses, which can lead to heart failure or fibrillation.

[3][1] The species' ability to be easily bred in captivity has led to a fall in prices within the free market, which is an alleviative factor to the problem of overharvesting.