In addition to translated material, Yen Press has published original series, most notably Svetlana Chmakova's Nightschool and a manga adaptation of James Patterson's Maximum Ride.

Yen Press was founded in 2006 by former Borders buyer Kurt Hassler and DC Comics VP Rich Johnson.

[6] In 2017, Yen Press launched JY, an imprint for publishing graphic novels aimed at middle-grade readers.

[7] On April 15, 2022, Yen Press, in collaboration with REDICE Studio and RIVERSE, launched Ize Press, an imprint for publishing Korean webtoons and novels, with their first titles being, 7Fates: Chakho, Dark Moon, and The Star Seekers all written and illustrated by HYBE in collaboration with BTS, Enhypen, and Tomorrow X Together respectively.

Other titles included were Tomb Raider King, The World After the Fall, The Boxer, My Gently Raised Beast, The Remarried Empress, and Villains Are Destined to Die.