Nicknamed the Whe Ho, the club were formed in 1886 and are based at Holm Park.

The club currently operate in the West of Scotland League Second Division and play in royal blue or orange strips.

Yoker were promoted to Central Division One on 23 April 2011 after an 8–0 victory over Newmains United.

The team was co-managed since January 2019 by Peter McKenna and Tommy Montgomery, Gordon Robertson took over as manager in 2022.

Yoker Athletic can boast of a mention in Scottish literature and film; James Kelman's novel, A Disaffection, has the main character attending a match at Holm Park, while the club is also mentioned briefly in an episode of Scottish cult classic Limmy's Show.