She also includes interview statements by non-celebrities, and celebrities, including All Things Considered anchor Susan Stamberg, Supreme Court Justice Ruth Bader Ginsburg, television sitcom producer Norman Lear and Mary Tyler Moore Show actor Ed Asner.

The film follows Berg's early years of marriage, her short period in New Orleans, her move to New York City, to her work in the radio and television renditions of The Goldbergs.

The film devotes attention to the role of The Goldbergs in helping to present a congenial image of a striving Jewish family to the broader American public, and the tremendous popularity that the radio and television shows experienced.

"[3] Yoo-Hoo, Mrs. Goldberg addresses developments contemporaneous with the years of The Goldbergs, Kristallnacht, the American Nazi German-American Bund and right-wing radio lecturer Father Coughlin.

It also deals with Berg's struggle against the McCarthy Era blacklisters and the influence of Red Channels.