Born in Shinjō, Yamagata[1][2] to a family that owned a paper shop,[3] Togashi began drawing manga casually in his first to second year of elementary school.

[4][5][6] Another manga by Togashi titled Jura no Mizuki (ジュラのミヅキ) was an honorable mention in Shueisha's first annual Hop Step Award Selection magazine, published in 1988.

[7] After having given up his goal of becoming a teacher, Togashi was contacted by an editor of Weekly Shōnen Jump during his senior year of college, who asked him to move to Tokyo.

An Ill-tempered Cupid in Heaven), a four-volume romance manga involving the relationship between a normal, human boy and a beautiful, devil girl.

Based on his interests in the occult and horror films, the plot features the character Yusuke Urameshi, who is killed and brought back to life as an "Underworld Detective".

The story revolves around the protagonist Gon Freecss, a young boy searching for his father, a legendary, elite member of society called a "Hunter".

[15] In 2008, Togashi tied with One Piece author Eiichiro Oda as the fifth favorite manga artist from a poll posted by the marketing research firm Oricon.

[4] Togashi suffered from an immense amount of stress while working on YuYu Hakusho, which caused him inconsistent sleep patterns and chest pain.

[23] On March 29, 2011, Togashi and his fellow manga artists posted messages on the official Shōnen Jump website in support of the victims of the 2011 Tōhoku earthquake and tsunami.

[29] Manga critic Jason Thompson stated that "Togashi is no ordinary mangaka; he does things his own way", furthering that his first one-shots were a mix of school comedy and "splatter-film horror references".

He then created the "0% fighting and 100% humor" science-fiction horror manga Level E.[30] Togashi's style of artwork began with screentone but gradually developed into minimalism.

[36][37] In 2012, Thompson speculated that Togashi's slow output was "because he's a perfectionist who enjoys his work and wants to do things himself", noting that his assistants could potentially be called upon further.

[38] In July 2022, Togashi revealed that he was unable to sit in a chair for two years due to his back and hip problems, but was able to resume drawing by doing so while lying down.