Dr. Stone (stylized as Dr.STONE) is a Japanese manga series written by Riichiro Inagaki and illustrated by the South Korean artist Boichi.

The story follows Senku Ishigami, a scientific genius who plans to rebuild civilization after humanity was mysteriously petrified for 3,700 years.

An anime television series adaptation produced by TMS Entertainment aired on Tokyo MX from July to December 2019.

A fourth and final season, titled Dr. Stone: Science Future, premiered in January 2025 and is scheduled to run for three split cours.

Senku sets up a base camp and begins to study the petrified humans in order to determine the cause of the event, as well as a cure.

They begin by reviving a famous high school martial artist named Tsukasa Shishio and their classmate Yuzuriha Ogawa with the goal of rebuilding civilization with a focus on science.

Tsukasa ultimately reveals that he opposes Senku's idea of forming a new scientific civilization, believing the old world was tainted and should not be restored.

After recovering from his near death experience, Senku discovers a tribe of people already living on the planet and sees this as an opportunity to create his Kingdom of Science.

Together with his new allies and friends, Senku's Kingdom of Science engages in a war with the Tsukasa Empire, ultimately emerging victorious and affirming themselves as a force to be reckoned with.

After the victory, they discover that Senku's adopted father had left precious metals which can be used as catalysts to mass-produce revival fluid in the nearby island which is now inhabited by a tribe known as the Petrification Kingdom, who possess the device used to petrify the world so long ago.

Riichiro Inagaki first began working on Dr. Stone with the initial idea of creating a protagonist that was considered a relatively normal character unlike many others within the genre.

[5] Inagaki was personally fascinated by the topic of science as a child and sought to create a science-based story for entertainment purposes that also featured common themes and messages that would be compelling for the audience.

[3] In regards to influences, Inagaki stated that Video Girl Ai was a series that had a significant impact on the story's development.

He settled upon the idea of creating a vast beautiful world in which Japan's nature was left untarnished due to the loss of humanity's influence.

[6] When asked about scientific accuracies, Inagaki revealed that both himself and Boichi have conducted research into the subject during the development of the series while also receiving help from a consultant.

[6] Director Shinya Iino expressed that one of the challenges with adapting the series into animation was determining how the backgrounds would appear in a different medium.

Boichi, who was looking for a story to work on, was approached around the time Inagaki (a fan of his art) finished the storyboards for chapter three.

[24] A nine-chapter spin-off, Dr. Stone Reboot: Byakuya, was published in Weekly Shōnen Jump from October 28 to December 23, 2019.

[29] A three-chapter spin-off, Dr. Stone: 4D Science, set after the main series finale, was published in Weekly Shōnen Jump from November 6 to December 25, 2023.

[32] The series is animated by TMS Entertainment, with Shinya Iino as director, Yuichiro Kido as scriptwriter, and Yuko Iwasa as character designer.

[56] The English dub of the anime began airing on Adult Swim's Toonami programming block on August 25, 2019.

list of top manga of 2018 for male readers,[68] and seventeenth, alongside Sweat and Soap and Heterogenia Linguistico, on the 2020 edition.