[3] In August 2015, Dagan was elected as Head of the Shomron Regional Council, replacing Gershon Mesika, who resigned from his post following a corruption scandal in the Yisrael Beiteinu political party.

[6] Following his military service, Dagan established a nucleus of religious families that joined the Sa-Nur Jewish community, that was subsequently destroyed in the course of Israel's 2005 Disengagement Plan.

In response, together with his friend Ariel Perel, Dagan organized and led a group of religious families to come to live in the Jewish community, thereby bolstering the number of residents for many years to come and helping to reinvigorate Sa-Nur.

When Sharon decided to implement the disengagement plan, despite the results of the referendum, Dagan led the struggle against the uprooting of Jewish communities in the Northern Shomron region.

As head of the Shomron Regional Council, Dagan continues to lead the call to return to the evacuated Jewish communities, promoting the subject in mass rallies, parliamentary work, and articles.

Among other things, he has published an article concerning a tree he planted in Sa-Nur before the evacuation, which he continues to tend to as a sign of hope for the reestablishment of all of the evicted Northern Shomron Jewish communities.

Dagan, who coined the phrase "the Jewish community movement's greatest enemy is ignorance," established the Shomron strategic information service that targeted both the Israeli and the foreign public.

As part of this activity, he established VIP tours to the Shomron, bringing more than 1,500 Israeli public opinion-makers to the region, among them important journalists, such as Avri Gilad, Menachem Ben, and Guy Zohar.

Following his participation in the tour, Avri Gilad announced on his radio program on the station Galei Tzahal that he had undergone a "paradigm shift" concerning the Jewish communities .

After Gershon Mesika resigned his post as Head of the Regional Council following a corruption scandal in the Yisrael Beiteinu political party, Dagan was appointed his successor.

Dagan is considered a key figure on the Israeli right, and has played crucial roles in political campaigns, including serving as a mediator between Prime Minister Netanyahu and Avigdor Lieberman in 2016.

His efforts resulted in Lieberman joining the government, thereby blocking the entrance of the Labor Party, then led by Isaac Herzog and Tzipi Livni[citation needed].

These lobbies organize meetings, tours, and conferences, as well as public events, at which figures such as the 14-year-old terror victim, Ayala Shapira, who was gravely injured in a December 2014 Molotov cocktail attack, have participated.

[10] After Trump's election, Dagan was invited as an official guest to the President's inauguration ceremony, the first Head of a Regional Council in Israel to receive such an honor.

Dagan even flew to Washington during President Trump and Prime Minister Netanyahu's announcement of the “Deal of the Century,” and pressed for the enactment of sovereignty in all the Jewish communities in the West Bank, and for a joint statement that a Palestinian State would never be established in the region.

[citation needed] In December 2020, together with businessmen in Dubai and the fam holding company, valued at more than NIS 3 billion, he announced an economic cooperation agreement for the export of wine, honey, olive oil and tahini manufacturers in Samaria to the United Arab Emirates.

In January 2015, Jewish settlers at the Adei Ad illegal outpost[19] threw stones at diplomats from a U.S. delegation who had arrived to inspect vandalism reported at a grove of Palestinian-owned trees in the occupied West Bank.

It was reported that recently, settlers were suspected of uprooting thousands of olive tree saplings, some of which had been planted in honor of senior Palestinian official Ziad Abu Ein, who collapsed and died after an altercation with an Israeli soldier.

[22] A U.S. State Department spokesman, Jeff Rathke, said, "We can confirm a vehicle from the Consulate General was pelted with stones and confronted by a group of armed settlers today in the West Bank, near the Palestinian village of Turmus Ayya."

Yossi Dagan, in his role as Head of the Shomron Regional Council, urged Interior Minister Gilad Erdan to expel the American delegation, claiming they were spies.

[27] In the end of October 2017 Yossi Dagan, Head of Shomron Regional Council led a three week long protest outside of the Prime Minister's Residence in Jerusalem.

This protest tent was established jointly by Dagan, Avi Naim, the Head of Beit Ariyeh Municipal Council, and Malachi Levinger, the mayor of Kiryat Arba.

Through cooperation and protection of the IDF command, the Shomron Regional Council organizes periodic visits and events at Joseph's Tomb in Nablus Shechem which in Area A under the full control of the Palestinian Authority.

On such a visit in December 2017 the site was found vandalized, something that has occurred repeatedly under the PA. Yossi Dagan called on the government of Israel to retake and protect the Jewish holy place.