Yotsuya Station (四ツ谷駅, Yotsuya-eki) is a railway station in the Yotsuya district of Shinjuku, Tokyo, Japan, operated jointly by East Japan Railway Company (JR East) and Tokyo Metro.

The JR East part of the station consists of two island platforms serving four tracks.

The station has a "Midori no Madoguchi" staffed ticket counter and "View Plaza" travel agency.

The station facilities of the Marunouchi and Namboku Lines were inherited by Tokyo Metro after the privatization of the Teito Rapid Transit Authority (TRTA) in 2004.

The Number of Passengers on Yotsuya as recorded by the East Japan Railway Company Trains in 2017-2022 was 25,896 (（単位　千人）).