"You Can't Stop the Reign" is the first single released from Shaquille O'Neal's third album, You Can't Stop the Reign.

The song was moderately successful, making it to 54 on the Hot R&B/Hip-Hop Singles & Tracks.

's verse would later be posthumously re-used on "Unbreakable", the opening track of Michael Jackson's 2001 album Invincible.

The song contains a sample of 1987 hit "You Can't Stop the Rain" by Loose Ends.

The album version was officially released onto streaming platforms as a single on June 14, 2024,[2] with the rest of the album being available two weeks later on June 28.