El Sherif played major roles in several TV series since 2011, firstly Citizen X in 2011, then Private Number in 2012, Temporary Name in 2013, The Hunter in 2014, The Devil's Game in 2015, The Caesar in 2016 and Kafr Delhab in 2017.

He collaborated with Atef in Private Number, The Hunter, The Caesar, The Devil's Game, Kafr Delhab, Sons Of Adam and The End.

He collaborated with Galal in Private Number, Temporary Name, The Hunter, The Caesar, The Devil's Game, Kafr Delhab and Sons Of Adam.

[6] In 2009, Youssef El-Sherif married the editor-in-chief of Euphoria magazine, Engy Alaa, and they have three children: the twins Abdelrahman and Abdallah as well as Jana.

[11] Youssef El Sherif stated more than once in television interviews that he places conditions in his business contracts by not providing "steamy scenes".