[3] Youth of May is set in the year 1980 during the Gwangju Uprising, follows the love story of medical student Hwang Hee-tae (Lee Do-hyun) and nurse Kim Myung-hee (Go Min-si).

Hwang Hee-tae (Lee Do-hyun) becomes the pride of Gwangju when he enters Seoul National University College of Medicine with top marks.

His best friend Kyung-soo (Kwon Young-chan), an avid pro-democracy activist, insists they open an illegal clinic for students on the run from the government.

In exchange for the costs of discreetly transporting himself and the factory worker to his hometown, Hee-tae must go to a meeting with a potential marriage partner arranged by his father.

[18] They were confirmed to star in the series on December 21, making it their second collaboration after Sweet Home (2020), along with Lee Sang-yi and Keum Sae-rok in the roles of siblings.