Except for Romancecar limited express services, all Odakyu Odawara Line trains stop at Yoyogi-Uehara.

Tokyo Metropolitan Route 413 ("Inokashira-dōri") intersects the Odawara Line just west of the station.

There are several music-related institutions including Koga Masao Museum of Music and JASRAC headquarters located nearby as well as the Tokyo Camii mosque.

The station was opened as a stop on the Odakyu Odawara Line on 1 April 1927.

TRTA (now Tokyo Metro) began service at the station on 31 March 1978.