After making her debut in The Tower of Druaga, she began serving as a script supervisor for several anime series and franchises, including Kin-iro Mosaic, Girls Beyond the Wasteland, The Seven Deadly Sins: Signs of Holy War, BanG Dream, The Idolmaster SideM, Given, D4DJ, and The Magical Girl and the Evil Lieutenant Used to Be Archenemies.
In 2008, while still a university student, Yuniko Ayana made her first screenwriting credit for the 2008 series The Tower of Druaga.
[5] Ayana was script supervisor and, alongside Ayumi Sekine [ja], co-scenario writer for Makura no Danshi, as well as story concept creator for Flip Flappers.
[25] She was the writer of Shigeyoshi Takagi [ja]'s manga Sore ga Sekai no Futsū ni Naru, and the two held an autograph session at the Animega store in Shinjuku Marui Annex on 28 February 2015.
[27] She also works in theatre, being the screenwriter for Butai: Sasayaku yō ni Koi wo Utau.