Born in the northern neighbourhood of Vila Cristina in São José dos Campos, Yuri Alberto joined Santos' youth setup in 2013 at the age of twelve.

[9] On 3 August 2020, after releasing a note two days earlier stating that the club "wished him success on his career playing for Santos",[10] Internacional announced the signing of Yuri Alberto on a five-year deal.

[11] The following 20 January, he scored a second-half hat-trick and made an assist in a 5–1 away routing of São Paulo, taking his tally up to ten league goals in only 16 matches.

[13] On 30 January 2022, Yuri Alberto signed a five-year deal with Russian Premier League club FC Zenit Saint Petersburg.

[15] In January 2023, he signed a permanent five-year deal with the Brazilian club, the transfer seeing Robert Renan and Du Queiroz moving in the opposite direction.