He was the son of the future governor of Riga prince Vladimir Petrovich (1699-1761) and Elena Vasilievna, née Princess Hilkova (died 1763).
Catherine II of Russia put him in command of a detachment sent in 1763 to support Stanisław August Poniatowski, a candidate for the throne of Poland.
Later, he was sent by Empress Catherine on a Russian mission to Montenegro when Šćepan Mali appeared on the scene claiming to be Peter III of Russia who died 1762.
Under Paul I of Russia he was military governor-general of Moscow and commander of the Astrakhan Grenadier Regiment.
After retirement he lived in a large lost house on the Bolshaya Nikitskaya and on his Moscow estate at Petrovskoe-Razumovskoye.