He was deputy chairman of the Central Bank of Russia from January 26 to August 1, 2022, and president of the International Association of Deposit Insurers from 2020 to 2022.

[3][4] Isaev occupied high-profile posts in the Russian business and financial institutions as well as government organisations in 2000-2020-s.

[5] From August 2003 to June 2004, Isaev served as chairman of the board of directors of Sheremetyevo International Airport.

[7] In January 2013, he resigned from the Duma before his term expired to work at the Deposit Insurance Agency of Russia.

From January 26, 2022 to August 1, 2022, Isaev served as deputy chairman of the Central Bank of the Russian Federation headed by Elvira Nabiullina.