His work focused on the pathology of the cornea.

In 1992, he was made a member of the Académie nationale de médecine.

In 1994 he was awarded the Prix mondial Cino Del Duca and on 29 November 2001 he was elected to the Académie Française.

[2] In 2000, Pouliquen was featured in the documentary film Vies.

[3][4] He was a member of the International Review Board of the Japanese Journal of Ophthalmology.