ZNF184

[6] The National Center for Biotechnology Information (NCBI) Gene database entry[5] for ZNF184 identifies conserved domains KRAB_A (Krüppel associated box) near the N-terminus and Zn-finger (Zinc finger) at the C-terminus of the translated protein.

The figure below is a reformatted and annotated conceptual translation display of ZNF184's Consensus CDS.

[8] CCDS displays exons in alternating black and blue font, with red indicating a residue coded across a splice boundary.

Light grey highlighted columns (one with all F; one with mostly L, and F substitutions) are highly conserved hydrophobic residues within the zinc finger motif.

The other light grey highlighted column (mostly K, with a similar R substitution) is an example of fairly strong conservation in the coil sections connecting adjacent fingers.

Reformatted Protein