The region was historically an agricultural area that cultivated various export products.

The population of Guatire has increased rapidly in recent years as an east suburb of Caracas.

Guatire, the municipality's shire town, is located near the western border.

[1] The municipality's population density in 2011 was 490 inhabitants per square kilometre (1,300/sq mi).

The mayor of the Zamora Municipality is Raziel Rodriguez, elected in 2021 for 2021-2025 tenure with 46,97% of the vote.