Zane Trace High School is a public high school near Chillicothe, Ohio, seated along the shores of Kinnikinnick Creek.

Their nickname is the Pioneers, and their colors are red, blue, and white.

The road followed historical Native American trails and passed by nearby Kinnikinnick Creek.

Zane Trace competes in the Scioto Valley Conference.

This Ross County, Ohio school-related article is a stub.