[3] In 1596 Zayzun appeared in the Ottoman tax registers as part of the nahiya (subdistrict) of Bani Juhma in the Qada of Hauran.

The northern side of the village stood at a higher elevation and held more importance than its southern counterpart.

Gardens of pomegranates, figs and other orchards laid to the north of the village and were irrigated by the Wadi al-Ajami stream.

[5] Schumacher noted that the village had recently flourished but had declined sharply by the time of his visit due to a blood feud between its sheikh (village headman) and the local Bedouin tribes, which forced the sheikh, his relatives and other residents to abandon Zayzun for the nearby Tell Shihab.

[5] Zayzun is the last stop of the secondary route of the Syrian Railways which primarily connect Damascus to Dera'a.