It flows through Tainan and Chiayi County.It is located in the southwestern part of the island.

Zéngwén is the pinyin romanization of the Mandarin pronunciation of the river's Chinese name 曾文溪.

It was formerly known as the Taiwanfu[4] from a former name of Tainan, when it was the headquarters of Qing administration on the island as a district of Fujian Province.

Taijiang National Park encompasses parts of the Zengwen estuary as well as nearby coastal areas.

[6] The endangered black-faced spoonbills come every winter as migrants and inhabit downstream near the estuary, where many other waterfowls are also found.