Zenker's degeneration

Zenker's degeneration is a severe glassy or waxy hyaline degeneration or necrosis of skeletal muscles in acute infectious diseases; a prototype of coagulative necrosis.

The condition was named by Friedrich Albert von Zenker.

It is a hyaline degeneration of skeletal muscles such as rectus abdominis and diaphragm, and occurs in severe toxaemia as typhoid fever.

[1] Grossly the muscles appear pale and friable; microscopically, the muscle fibres are swollen, have a loss of cross striations, and show a hyaline appearance.

This article about a disease of musculoskeletal and connective tissue is a stub.