He received master's degrees in architecture and in city planning from the University of Pennsylvania, Graduate School of Fine Arts in 1972.

[4] At the beginning of his career, Mazurkevich worked for Ludwig Mies van der Rohe, as well as the architectural firm of Skidmore Owings and Merrill, where he was involved with the design of the 100-story John Hancock Center in Chicago, Illinois.

His most prominent architectural work is St. Joseph the Betrothed Ukrainian Catholic Church in Chicago, Illinois.

[14] Mazurkevich's other projects included St. Michael the Archangel Ukrainian Catholic Church in Baltimore, Maryland, which he designed in the Cossack Baroque style, the Prayer Room at St.

Basil Academy in Fox Chase, Pennsylvania, the Order of St. Basils Monastery in Glen Cove, New York, renovations of St. Nicholas Ukrainian Catholic Cathedral in Chicago, Illinois,[15] as well as an avant-garde design for the Cathedral of the Transfiguration of our Lord, in Kolomyia, Ukraine.