The rhizome of variant 'Roxburgh' is used medicinally in massage and even in food in Thailand, and somewhat resembles ginger root or galangal.

[3] In addition, an American study found that plai oil exhibits antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria, dermatophytes, and yeasts.

[4] A study also showed essential oil from Z. cassumunar had anti-microbial activity against XDR Acinetobacter baumannii and synergized with medically useful antibiotics.

[5] Finally, a 1992 study discovered the zerumbone contained in the rhizomes of the plant has antifungal properties against pathogenic fungi.

[6] The plant also contains the essential oils sabinene 31–48%, terpineol 4–30%,[2] and apparently unique curcuminoid antioxidants, namely cassumunarin types A, B, and C.[7]