In 1709, when Patriarch of Alexandria Gerasimos Palladas visited the court of Prince Constantin Brâncoveanu, the monastery, and its surrounding inn were subordinated to his church.
[1] The church suffered severe damage during the 1802 and 1838 earthquakes, and was entirely rebuilt starting in 1850, as recorded by the 1860 pisanie, also in Greek; reportedly, Xavier Villacrosse was the architect.
A fresco depicting the Nativity of the Virgin and an inscription submitting to Alexandria were discovered at the time, but later lost.
Until the late 1970s, the church stood alone between Lipscani and Stavropoleos Streets, with green space covering the inn's foundation.
Aside from the central dome, there are four smaller ones atop the nave corners; these are octagonal, resting on square bases.