She had a supporting role, as Amalindis, in the Swiss television feature film Die Hexenprinzessin in 2020.
[4][1] She became familiar with social media when she was started creating online content for the dance academy she was enrolled in.
[4][1] Holthuizen began her career as a stage actress, performing in plays at the European Film Actor School including Die Möve, Die drei Schwestern, Blick zurück im Zorn, and Late Night Talk.
[1][4] In 2017 Holthuizen had a lead supporting role as Gianna in Lisa Brühlmannthe's coming-of-age film Blue My Mind.
[12] In 2020 Holthuizen had a supporting lead role as Amalindis in the Swiss television feature film Die Hexenprinzessin.