Her first roles included an angel in Heggie's It's a Wonderful Life, Flora Bervoix in Verdi's La traviata and Mao's third secretary in Adam's Nixon in China.
At the Wolf Trap Opera she has been seen and heard in rarely performed works by Gioachino Rossini and John Musto.
In the 2023/24 season she returned to the Minnesota Opera — as Dinah in Bernstein's Trouble in Tahiti and as Autumn in Service Provider by Christopher Weiss and John de los Santos.
[6] The singer has been lauded by Opera News for her “velvety mezzo” and for how she “phrase[s] with elegance and articulate[s] coloratura nimbly.”[5] Zoie Reams can also be heard regularly in concert halls.
For example, she sang the alto solos in Beethoven's Ninth (with the National Symphony Orchestra),[5] Bruckner's Te Deum (with the Houston Symphony),[5] Michael Tippett's A Child of Our Time (with the New York Choral Society) at New York's Carnegie Hall,[5] Bernstein's Jeremiah Symphony (with the Philharmonic Orchestra of the State Theater Cottbus)[5] and Handel's Messiah in Las Vegas, Kansas City and at the Washington National Cathedral.