The Zomandao River is a 283-km-long river in the regions of Haute Matsiatra and Ihorombe in central-southern Madagascar.

It begins in the Andringitra Massif at Boby Peak,[1] the second highest peak of Madagascar, and flows across the Zomandao Plain.

It is one of the main tributaries of the Mangoky River.

A main attribute to the Zomandao River is the Ihosy River.

This article related to a river in Madagascar is a stub.