It is a tributary of the Tsiribihina River.

The Sakeny originates on the northern Makay Massif in northern Beroroha District of Atsimo-Andrefana Region.

It flows northward through the north–south running Betsiriry plain of Menabe Region, between Madagascar's Central Highlands on the east and the lower limestone Bemaraha Plateau on the west.

There are extensive seasonal wetlands at the confluence.

This article related to a river in Madagascar is a stub.