A press release on the film stated that it "uses comedy, the zombie genre and '90s nostalgia as a vehicle, to comment on pop-culture as much as it feeds it".

[2] Undercover agent Vanilla Ice, who trained under Commander Chuck Norris, uses his skill set to dispatch a plane overrun by the undead before fighter jets can neutralise it to save humanity from a zombie outbreak.

[1] The Hollywood Reporter and Entertainment Weekly jointly announced on 16 October 2023 that Chuck Norris, Vanilla Ice, and Sophie Monk would be playing themselves in Zombie Plane, an action comedy film which was directed by Australian filmmakers Lav Bodnaruk and Michael Mier.

[1] Mier said that the idea for the film was inspired by a TMZ episode screenwriter William Strong had seen, in which Ice told the reporter that some kind of biohazard had caused his flight to be grounded.

The script employs self-referential humour that "mercilessly mocks its main stars": for example, Monk spends a considerable amount of time deriding Ice's career in the film, at one point referring to him as "a one-hit wonder and a has-been".