Ayala amassed an 8–0 record before being booked to face Luis Castro for the vacant WBC FECARBOX flyweight title on 16 October 2020.
[2] Ayala made his first regional title defense against Jeovani Gonzalez on 22 January 2022, on the undercard of the Hector Flores and Juan Carlos Parra light flyweight bout.
[3] Ayala faced the overmatched Brandon "Gallardo" Vargas (3–2–1) for the vacant ABF Continental Americas flyweight title on 30 April 2021.
[5] His eleven-fight undefeated streak earned Ayala the chance to face Cristofer Rosales in a WBC flyweight title eliminator.
It was scheduled as the main event of an Azteca 7 broadcast card, which took place at Centro de Espectáculos del Recinto Ferial in Metepec, Mexico on 9 April 2022.