It was likely founded by Hilary of Arles at the beginning of the 5th century, "in insula suburbana civitatis" defining the Isle of Gallègue as the location.

[2] This church was probably ruined by the conflict around the years 470-508, and was transferred a century later, in 546 or 547, to the left bank of the Rhône, in the Vieux-Bourg, in the reign of Childebert I and the archbishop Aurelianus of Arles.

[3] During the Middle Ages, except possibly at the beginning of the ninth century, this area was totally abandoned and there is no evidence of a church.

A second church was built in the quarter of "la Pointe" (to the north of Trinquetaille, where the Rhône separates into two streams), probably during the twelfth century.

The House of Baux possessed a strong castle at Trinquetaille at the beginning of the twelfth century and this may have included the church.