1,3-Dibromopropane

It is used in organic synthesis to form C3-bridged compounds such as through C-N coupling reactions.

[6] The examination was done by orally administering 1,3-dibromopropane to rats and collecting results 24 hours after administration.

Results were obtained from three sources: urine, faeces, and expired air.

Upon analysis of the urinary results, researchers discovered the formation of metabolite, N-acetyl-S-(1-bromo-3-propyl)-cysteine and the decline in the GSH content of the liver of the rats.

This led to the assumption that 1,3-dibromopropane could have reacted with GSH after administration and gave rise to 1-bromo-3-propyl-S-glutathione, which ultimately form the urinary metabolite.

Skeletal formula of 1,3-dibromopropane
Skeletal formula of 1,3-dibromopropane
Ball and stick model of 1,3-dibromopropane
Ball and stick model of 1,3-dibromopropane
Spacefill model of 1,3-dibromopropane
Spacefill model of 1,3-dibromopropane